Selective expression of gastric mucin MUC6 in colonic sessile serrated adenoma but not in hyperplastic polyp aids in morphological diagnosis of serrated polyps
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چکیده
منابع مشابه
Sessile serrated adenoma/polyps with a depressed surface: a rare form of sessile serrated adenoma/polyp
Sessile serrated adenoma/polyps (SSA/Ps) usually appear flat to sessile with a smooth-appearing surface. However, macroscopic appearances of SSA/P can vary from flat-elevated to nodular and can even show a pedunculated configuration as we previously reported. The aim of the current study was to evaluate the clinicopathologic features of another under-recognized form of SSA/P which shows a depre...
متن کاملSessile serrated lesion misdiagnosed as a hyperplastic polyp.
An 81-year-old woman presented for colonoscopy because of iron deficiency anemia. She had undergone colonoscopy 5 years previously during which a 2-cm prominent fold had been identified in the proximal ascending colon (●" Fig.1). A biopsy of this lesion was interpreted as being a hyperplastic polyp (●" Fig.2), although the polyp showed features of a serrated lesion. Because of clinical concern ...
متن کاملSessile serrated adenoma/polyps: Where are we at in 2016?
It is currently known that colorectal cancers (CRC) arise from 3 different pathways: the adenoma to carcinoma chromosomal instability pathway (50%-70%); the mutator "Lynch syndrome" route (3%-5%); and the serrated pathway (30%-35%). The World Health Organization has classified serrated polyps into three types of lesions: hyperplastic polyps (HP), sessile serrated adenomas/polyps (SSA/P) and tra...
متن کاملProspective evaluation of the proportion of sessile serrated adenoma/polyps in endoscopically diagnosed colorectal polyps with hyperplastic features1
BACKGROUND AND STUDY AIMS Sessile serrated adenoma/polyps (SSA/Ps) are considered precursors of colorectal cancers with microsatellite instability. However, it is still difficult to differentiate SSA/Ps from hyperplastic polyps endoscopically; therefore, the prevalence of SSA/Ps remains uncertain in clinical practice. This study aimed to clarify the proportion of SSA/Ps in endoscopically diagno...
متن کاملOptimizing resection of sessile serrated polyps.
Removal of precancerous lesions during colonoscopy reduces colorectal cancer (CRC) incidence and mortality [1]. Recent data have highlighted that interval CRC occurs despite previous colonoscopy. Incomplete removal of polyps is one of the factors leading to interval CRCs [2]. Incomplete polypectomy of sessile serrated polyps (SSPs) is four-fold higher than that of conventional adenomas [3] and ...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2008
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.2008.55